Epigenetics in human autoimmunity

Role of Epigenetics in Biology and Human Diseases

For a long time, scientists have tried to describe disorders just by genetic or environmental factors. However, the role of epigenetics in human diseases has been considered from a half of century ago. In the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

Epigenetics in human melanoma.

BACKGROUND Recent technological advances have allowed us to examine the human genome in greater detail than ever before. This has opened the door to an improved understanding of the gene expression patterns involved with cancer. METHODS A review of the literature was performed to determine the role of epigenetic modifications in human melanoma. We focused the search on histone deacetylation, ...

Epigenetics and Human Disease.

Genetic causes for human disorders are being discovered at an unprecedented pace. A growing subclass of disease-causing mutations involves changes in the epigenome or in the abundance and activity of proteins that regulate chromatin structure. This article focuses on research that has uncovered human diseases that stem from such epigenetic deregulation. Disease may be caused by direct changes i...

Epigenetics and Human Disease

Although the term epigenetics has been around for more than 50 years, it is perhaps not surprising that there have been several revisions to its definition. Originally used to describe the cascade of changes within an organism associated with growth and development that are directed by both the organism's genome and i ts surrounding environment, the term now refers to potentially heritable info...

Epigenetics and Human Health